Rune of Self-sacrifice

The Rune of Self-sacrifice is a rune added by Blood Magic that is used to upgrade the tier of the Blood Altar. It can be used in place of other runes, and can work alongside each rune in the upgrade process. Each Rune of Self-sacrifice increases the total amount of LP gained by 20 when using the Sacrificial Knife.

Recipe
The Blood Orb is not consumed in this process.